HIV Prevention Trials Network - HPTN

The HIV Prevention Trials Network (HPTN) is a worldwide collaborative clinical trials network that develops and tests the safety and efficacy of primarily non-vaccine interventions designed to prevent the transmission of HIV.  Established in 1999 by the Division of AIDS of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, HPTN focuses its research agenda on anti-retroviral therapy, microbicides, perinatal prevention, sexual behavior, substance use, and sexually transmitted infections.  HPTN carries out its mission through a strong network of expert scientists and investigators from more than two dozen international sites partnered with a leadership group comprised of three U.S.-based institutions.  

FHI serves as the Coordinating and Operations Center (CORE) for HPTN.  As the CORE, FHI is responsible for scientific management of HPTN, starting with research plan development and continuing through protocol review, study implementation, and publication of results. FHI also is responsible for logistical, administrative, and communications support for HPTN committees, scientific working groups, protocol teams, and Community Advisory Boards. FHI works closely with DAIDS Program and Grants Management staff on monitoring and resource allocation within the Network, including the management of the HPTN discretionary fund.

Recent research

Nevirapine Sustains Advantage Over AZT During Breastfeeding Period